The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.

Eigner K, Filik Y, Mark F, Schütz B, Klambauer G, Moriggl R, Hengstschläger M, Stangl H, Mikula M, Röhrl C.

Sci Rep. 2017 Dec 13;7(1):17498


HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study.

Plochberger B, Röhrl C, Preiner J, Rankl C, Brameshuber M, Madl J, Bittman R, Ros R, Sezgin E, Eggeling C, Hinterdorfer P, Stangl H, Schütz GJ.

Sci Rep. 2017 Nov 21;7(1):15886.


Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation.

Kinslechner K, Schörghofer D, Schütz B, Vallianou M, Wingelhofer B, Mikulits W, Röhrl C, Hengstschläger M, Moriggl R, Stangl H, Mikula M.

Mol Cancer Res. 2017 Oct 3. doi: 10.1158/1541-7786.MCR-17-0292


The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability.

Wang L, Palme V, Schilcher N, Ladurner A, Heiss EH, Stangl H, Bauer R, Dirsch VM, Atanasov AG.

Front Pharmacol. 2017 Sep 1;8:596.


Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc, a System L Amino Acid Transporter.

Balthasar C, Stangl H, Widhalm R, Granitzer S, Hengstschläger M, Gundacker C.

Int J Mol Sci. 2017 Aug 8;18(8).


Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages.

Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, Ladurner A, Heiss EH, Stangl H, Dirsch VM, Atanasov AG.

Mol Nutr Food Res. 2017 Apr;61(4).




Moderate alcohol consumption shifts to an atheroprotective phenotype: A glass of wine keeps atherosclerosis in check?

Schernthaner GH, Herz C, Stangl H.

Atherosclerosis. 2016 Nov;254:305-306.


The unfolded protein response is a negative regulator of scavenger receptor class B, type I (SR-BI) expression.

Eberhart T, Eigner K, Filik Y, Fruhwürth S, Stangl H, Röhrl C.

Biochem Biophys Res Commun. 2016 Oct 21;479(3):557-562.


Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages.

Wang L, Ladurner A, Latkolik S, Schwaiger S, Linder T, Hošek J, Palme V, Schilcher N, Polanský O, Heiss EH, Stangl H, Mihovilovic MD, Stuppner H, Dirsch VM, Atanasov AG.

J Nat Prod. 2016 Jun 24;79(6):1651-7.


Potential of BODIPY-cholesterol for analysis of cholesterol transport and diffusion in living cells.

Wüstner D, Lund FW, Röhrl C, Stangl H.

Chem Phys Lipids. 2016 Jan;194:12-28.


Effect of chronic kidney disease on macrophage cholesterol efflux.

Meier SM, Wultsch A, Hollaus M, Ammann M, Pemberger E, Liebscher F, Lambers B, Fruhwürth S, Stojakovic T, Scharnagl H, Schmidt A, Springer A, Becker J, Aufricht C, Handisurya A, Kapeller S, Röhrl C, Stangl H, Strobl W.

Life Sci. 2015 Sep 1;136:1-6.


The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence.

Schörghofer D, Kinslechner K, Preitschopf A, Schütz B, Röhrl C, Hengstschläger M, Stangl H, Mikula M.

Reprod Biol Endocrinol. 2015 Aug 7;13:88.


Profound Changes in Sex Hormone Levels during Cross-Sex Hormone Therapy of Transsexuals do not Alter Serum Cholesterol Acceptor Capacity.

Wultsch A, Kaufmann U, Ott J, Stojakovic T, Scharnagl H, Stangl H, Strobl WM.

J Sex Med. 2015 Jun;12(6):1436-9.


2-Deoxy-D-glucose treatment changes the Golgi apparatus architecture without blocking synthesis of complex lipids.

Ranftler C, Meisslitzer-Ruppitsch C, Stangl H, Röhrl C, Fruhwürth S, Neumüller J, Pavelka M, Ellinger A.

Histochem Cell Biol. 2015 Apr;143(4):369-80.




mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression.

Preitschopf A, Li K, Schörghofer D, Kinslechner K, Schütz B, Thi Thanh Pham H, Rosner M, Joo GJ, Röhrl C, Weichhart T, Stangl H, Lubec G, Hengstschläger M, Mikula M.

PLoS One. 2014 Sep 15;9(9):e107004.


Differential basolateral-apical distribution of scavenger receptor, class B, type I in cultured cells and the liver.

Fruhwürth S, Kovacs WJ, Bittman R, Messner S, Röhrl C, Stangl H.

Histochem Cell Biol. 2014 Dec;142(6):645-55.


Bile acids reduce endocytosis of high-density lipoprotein (HDL) in HepG2 cells.

Röhrl C, Eigner K, Fruhwürth S, Stangl H.

PLoS One. 2014 Jul 10;9(7):e102026.


Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production.

Fruhwürth S, Krieger S, Winter K, Rosner M, Mikula M, Weichhart T, Bittman R, Hengstschläger M, Stangl H.

Biochim Biophys Acta. 2014 Jul;1841(7):944-53.


Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells.

Röhrl C, Eigner K, Winter K, Korbelius M, Obrowsky S, Kratky D, Kovacs WJ, Stangl H.

J Lipid Res. 2014 Jan;55(1):94-103.



HDL endocytosis and resecretion.

Röhrl C, Stangl H.

Biochim Biophys Acta. 2013 Nov;1831(11):1626-33.


High-density lipoprotein endocytosis in endothelial cells.

Fruhwürth S, Pavelka M, Bittman R, Kovacs WJ, Walter KM, Röhrl C, Stangl H.

World J Biol Chem. 2013 Nov 26;4(4):131-40.


Reduced adiponectin receptor signalling accelerates atherosclerosis and may worsen the outcome in type 2 diabetes mellitus - another one of those missing links?

Schernthaner GH, Stangl H.

Atherosclerosis. 2013 Jul;229(1):30-1.


Photooxidation technology for correlative light and electron microscopy.

Meisslitzer-Ruppitsch C, Röhrl C, Ranftler C, Stangl H, Neumüller J, Pavelka M, Ellinger A.

Methods Mol Biol. 2013;931:423-36.



Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype.

Cardilo-Reis L, Gruber S, Schreier SM, Drechsler M, Papac-Milicevic N, Weber C, Wagner O, Stangl H, Soehnlein O, Binder CJ.

EMBO Mol Med. 2012 Oct;4(10):1072-86.


Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles.

Röhrl C, Meisslitzer-Ruppitsch C, Bittman R, Li Z, Pabst G, Prassl R, Strobl W, Neumüller J, Ellinger A, Pavelka M, Stangl H.

Curr Pharm Biotechnol. 2012 Feb;13(2):331-40.



A combination of (ω-3)polyunsaturated fatty acids, polyphenoles and L-carnithine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation inhuman peripheral blood mononuclear cells and HepG2 cells.

Radler U, Stangl H, Lechner S, Lienbacher G, Krepp R, Zeller E, Brachinger M, Eller-Berndl D, Fischer A, Anzur C, Schoerg G, Mascher D, Laschan C, Anderwald C, Lohninger A.

Ann Nutr Metab. 2011;58(2):133-40.

Effect of obesity on plasma clusterin, [corrected] a proposed modulator of leptin action.

Arnold T, Brandlhofer S, Vrtikapa K, Stangl H, Hermann M, Zwiauer K, Mangge H, Karwautz A, Huemer J, Koller D, Schneider WJ, Strobl W.

Pediatr Res. 2011 Mar;69(3):237-42. doi: 10.1203/PDR.0b013e31820930cb. Erratum in: Pediatr Res. 2011 Apr;69(4):358.





Effect of Obesity on Plasma Clusterin, a Proposed Modulator of Leptin Action.

Arnold T, Brandlhofer S, Vrtikapa K, Stangl H, Hermann M, Zwiauer K, Mangge H, Karwautz A, Huemer J, Koller D, Schneider WJ, Strobl W.

Pediatr Res. 2011 Mar;69(3):237-42. Erratum in: Pediatr Res. 2011 Apr;69(4):358.


The ceramide-enriched trans-Golgi compartments reorganize together with other parts of the Golgi apparatus in response to ATP-depletion.

Meisslitzer-Ruppitsch C, Röhrl C, Ranftler C, Neumüller J, Vetterlein M, Ellinger A and Pavelka M

Histochem Cell Biol. 2010 Mar;133(3):261-72.


Characterization of endocytic compartments after holo-high density lipoprotein particle uptake in HepG2 cells.

Röhrl C, Pagler TA, Strobl W, Ellinger A, Neumüller J, Pavelka M, Stangl H, Meisslitzer-Ruppitsch C

Histochem Cell Biol. 2010 Mar; 133(3):261-72.


Scavenger receptor, Class B, Type I provides an alternative means for beta-VLDL uptake independent of the LDL receptor in tissue culture.

Röhrl C, Fruhwürth S, Schreier SM, Lohninger A, Dolischka A, Hüttinger M, Zemann N, Hermann M, Strobl W, Stangl H.

Biochim Biophys Acta. 2010 Feb; 1801(2):198-204. 




Photooxidation technology for correlated light and electron microscopy.

Meisslitzer-Ruppitsch C, Röhrl C, Neumüller J, Pavelka M, Ellinger A.

J Microsc. 2009 Sep;235(3):322-35.


Atherogenic diet leads to posttranslational down-regulation of murine hepatocyte SR-BI expression.

Niemeier A, Kovacs WJ, Strobl W, Stangl H.

Atherosclerosis. 2009 Jan;202(1):169-75.




Electron microscopic visualization of fluorescent signals in cellular compartments and organelles by means of DAB-photoconversion.

Meisslitzer-Ruppitsch C, Vetterlein M, Stangl H, Maier S, Neumüller J, Freissmuth M, Pavelka M, Ellinger A.

Histochem Cell Biol. 2008 Aug;130(2):407-19


Changes in hepatic ApoAV expression are not required for the rapid triglyceride lowering effect of fish oil diet in rats.

Hagerty BP, Schaap FG, Hermann M, Krenn B, Eder C, Dorfmeister B, Stangl H, Patsch W, Strobl W.

Horm Metab Res. 2008 Jan;40(1):69-71




Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaired.

Pagler TA, Neuhofer A, Laggner H, Strobl W, Stangl H.

J Lipid Res. 2007 Oct;48(10):2141-50




A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.

Pagler TA, Golsabahi S, Doringer M, Rhode S, Schütz GJ, Pavelka M, Wadsack C, Gauster M, Lohninger A, Laggner H, Strobl W, Stangl H.

J Biol Chem. 2006 Dec 15;281(50):38159-71. 


Peroxisomal cholesterol biosynthesis and Smith-Lemli-Opitz syndrome.

Weinhofer I, Kunze M, Stangl H, Porter FD, Berger J.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):205-9


A combined optical and atomic force microscope for live cell investigations.

Madl J, Rhode S, Stangl H, Stockinger H, Hinterdorfer P, Schütz GJ, Kada G.

Ultramicroscopy. 2006 Jun-Jul;106(8-9):645-51.


Apolipoprotein AV does not contribute to hypertriglyceridaemia or triglyceride lowering by dietary fish oil and rosiglitazone in obese Zucker rats.

Dorfmeister B, Brandlhofer S, Schaap FG, Hermann M, Fürnsinn C, Hagerty BP, Stangl H, Patsch W, Strobl W.

Diabetologia. 2006 Jun;49(6):1324-32. 


SR-BI-mediated high density lipoprotein (HDL) endocytosis leads to HDL resecretion facilitating cholesterol efflux.

Pagler TA, Rhode S, Neuhofer A, Laggner H, Strobl W, Hinterndorfer C, Volf I, Pavelka M, Eckhardt ER, van der Westhuyzen DR, Schütz GJ, Stangl H.

J Biol Chem. 2006 Apr 21;281(16):11193-204.